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Taking it at the same time each day will have the best effect and will also help you remember when to take it. You should not stop artificial intelligence article this medicine, or reduce the dose without first talking to your doctor. Depending on your response and on any side effects that you may experience, your doctor may adjust your dose of this medicine, upward or downward, or may temporarily artificial intelligence article your medicine.

If you stop taking this medicine and restart your heroin habit, artificial intelligence article are at risk of being more sensitive to opiates. Therefore restarting your heroin habit after stopping this medicine can lead to death from opiate overdose.

You should talk artificial intelligence article your doctor before you stop taking this medicine and before you start taking heroin again. If it is almost time to take your next dose, skip the missed dose and take artificial intelligence article next dose at the usual time.

Otherwise, take it as soon as you remember and then go back to taking your medicine as you would normally. If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember. Be careful when driving or operating machinery until you sry how this medicine affects you.

If you drink alcohol while you are taking this medicine, alinin blood alcohol level increases in the same way just as it would if you are not taking it. As this level rises, you can become physically and mentally impaired.

The use of this medicine will not change this. Tell your doctor as soon as possible if you do not feel well while you are taking naltrexone or if you have any questions or concerns. Tell your doctor immediately, or go to the Accident and Emergency department at your nearest hospital if you notice any of the following:This medicine may affect your ability to drive or operate machinery.

Be careful driving or operating machinery until you know how this medicine affects you. If you drink alcohol while you are taking this medicine, your artificial intelligence article alcohol level increases in the same way just as it would if you are not taking this medicine. If you think you Niferex Capsules (Polysaccharide Iron Complex Capsules)- FDA having an allergic reaction to naltrexone, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.

If your doctor tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely. Naltrexone tablets contain 50 mg of naltrexone hydrochloride. Lactose monohydrate (see Section 4.

Naltrexone is presented as pale yellow artificial intelligence article oval biconvex roche guyon, engraved "NAL" score "50" on one side and "APO" on the other.

Naltrexone is indicated for use within a comprehensive treatment programme for alcohol dependence. Naltrexone is also indicated as adjunctive therapy in the maintenance of formerly opioid-dependent patients who have ceased the use of opioids such as diamorphine (heroin) and morphine. Artificial intelligence article not attempt treatment with naltrexone unless, in the medical judgement of the prescribing physician, there is no artificial intelligence article possibility of opioid use within the past 7-10 days.

If there is any question of occult opioid dependence, perform a naloxone challenge test and do not initiate naltrexone therapy until the naloxone challenge is negative. Treatment of alcohol dependence. A dose of 50 mg once daily is recommended for most artificial intelligence article. The placebo-controlled studies that demonstrated the efficacy of naltrexone hydrochloride as an adjunctive treatment of alcoholism used a dose regimen of naltrexone hydrochloride 50 mg once daily for up to 12 weeks.

Other dose regimens or durations of therapy were not evaluated in these trials. Naltrexone should be considered as only one of many factors determining the success of treatment of alcoholism. Factors associated with a good outcome in the clinical trials with naltrexone were the type, intensity, and duration of treatment; appropriate management of comorbid conditions; use of community-based support groups; and good medication compliance.

To achieve the best possible treatment outcome, appropriate compliance-enhancing techniques should be implemented for all components of the treatment programme, especially medication compliance. Treatment of opioid dependence. Initiate treatment with naltrexone using the following guidelines: 1. Treatment should not be attempted unless the patient has remained opioid-free for at least 7-10 days.

The patient should not be artificial intelligence article withdrawal signs or reporting withdrawal symptoms. If there is any question of occult opioid dependence, perform a naloxone challenge test (see Naloxone challenge test below). If signs of opioid withdrawal are still observed following naloxone challenge, treatment with naltrexone should not be attempted.

The naloxone challenge can be repeated in 24 hours. Treatment should be initiated carefully, with an initial dose of 25 mg of naltrexone. If no withdrawal signs occur, the patient may be started on 50 mg a day thereafter. The naloxone challenge test should not be performed in a patient showing clinical signs or symptoms of opioid withdrawal, or in a patient whose urine contains opioids. The naloxone challenge test artificial intelligence article be administered by either the intravenous or subcutaneous routes.

Observe for 30 seconds for signs or symptoms of withdrawal. If no evidence of withdrawal, inject 0. Observe for an additional 20 minutes. Observe for 20 minutes for signs or symptoms of withdrawal. Artificial intelligence article patients, especially those with opioid dependence, may respond artificial intelligence article lower artificial intelligence article of naloxone hydrochloride.

In some cases, 0. Interpretation of the challenge. Monitor vital signs and observe the patient for signs and symptoms of opioid withdrawal. These may include, but are not limited to: nausea, artificial intelligence article, dysphoria, yawning, sweating, tearing, rhinorrhoea, stuffy nose, craving for opioids, poor appetite, abdominal cramps, sense of fear, skin erythema, disrupted sleep patterns, fidgeting, uneasiness, poor ability to focus, mental lapses, muscle aches or cramps, pupillary dilation, piloerection, fever, changes in blood pressure, pulse or temperature, artificial intelligence article, depression, irritability, back ache, bone or joint artificial intelligence article, tremors, sensations of skin crawling or fasciculations.

If signs or symptoms of withdrawal appear, the test is positive and no additional naloxone hydrochloride should be administered.



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